Analytical Electrogenerated Chemiluminescence

From Fundamentals to Bioassays

Edited by Neso Sojic

Publication date:

15 November 2019

Length of book:

501 pages

Publisher

Royal Society of Chemistry

ISBN-13: 9781839160066

Electrogenerated chemiluminescence (ECL) is a powerful and versatile analytical technique, which is widely applied for biosensing and successfully commercialized in the healthcare diagnostic market. After introducing the fundamental concepts, this book will highlight the recent analytical applications with a special focus on immunoassays, genotoxicity, imaging, DNA and enzymatic assays. The topic is clearly at the frontier between several scientific domains involving analytical chemistry, electrochemistry, photochemistry, materials science, nanoscience and biology. This book is ideal for graduate students, academics and researchers in industry looking for a comprehensive guide to the different aspects of electrogenerated chemiluminescence.

Introduction and Overview of Electrogenerated Chemiluminescence; Energetic and Kinetic Aspects of ECL Generation; Efficient ECL Luminophores; Electrochemiluminescence Coreactants; Theoretical Concepts Underlying ECL Generation; The Essential Role of Electrode Materials in ECL Applications; Wireless ECL Generation Based on Bipolar Electrochemistry; Multicolour Electrochemiluminescence; ECL of Nanomaterials: Novel Materials, Detection Strategies and Applications; ECL Detection of Nanoparticles; Single Entity Electrogenerated Chemiluminescence; Enzymatic Assays; DNA-based ECL Assays; Microfluidic ECL and Voltammetric Arrays for Metabolite-related DNA Damage; Automated Immunoassays for the Detection of Biomarkers in Body Fluids; Electrochemiluminescence Imaging

The book is well developed, and the topic is presented with a clear logic. The present book is a needed contribution, it allows to easily access the topic and provides comprehensive insights of both the theoretical aspects and recent technological advancement. It provides a unique resource of information and a reference point to researchers in the physical, chemical, and biological sciences.