Quenched-phosphorescence Detection of Molecular Oxygen

Applications in Life Sciences

Edited by Dmitri B Papkovsky, Ruslan I Dmitriev

Publication date:

25 May 2018

Length of book:

368 pages

Publisher

Royal Society of Chemistry

ISBN-13: 9781788013451

BOOK DESCRIPTION
TABLE OF CONTENTS

Significant progress has been made in recent years in quenched-phosphorescence oxygen sensing, particularly in the materials and applications of this detection technology that are open to commercialization, like uses in brain imaging and food packaging. Prompted by this, the editors have delivered a dedicated book that brings together these developments, provides a comprehensive overview of the different detection methodologies, and representative examples and applications.

This book is intended to attract new researchers from various disciplines such as chemistry, physics, biology and medicine, stimulate further progress in the field and assist in developing new applications. Providing a concise summary at the cutting edge, this practical guide for current experts and new potential users will increase awareness of this versatile sensing technology.

Fundamentals of quenched phosphorescence O2 sensing and rational design of sensor materials; New polymer-based sensor materials and fabrication technologies for large-scale applications; Evolution of Cell-Penetrating Phosphorescent O2 Probes; Hydrophilic Ir(III) complexes for in vitro and in vivo oxygen imaging; Protection of triplet excited state materials from oxygen quenching and photooxidation in optical sensing applications; Progress in phosphorescence lifetime measurement instrumentation for oxygen sensing; Optical O2 sensing in aquatic systems and organisms; Monitoring of extracellular and intracellular O2 on a time-resolved fluorescence plate reader; Monitoring parameters of oxygen transport to cells in the microcirculation; Photoacoustic imaging of oxygen; Imaging of Tissue Oxygen Ex Vivo; Tracking of Hypoxia and Cancer Metastasis with Iridium(III)-based O2 Probes; Probing Tissue Oxygenation by Delayed Fluorescence of Protoporphyrin IX; Microfluidic systems and optical oxygen sensors: A perfect match for advancing bioprocessing and microbiology; pO2 measurements in biological tissues by luminescence lifetime spectroscopy: Strategies to exploit or minimize phototoxic effects in tumors; In Vivo Brain Functional Imaging Using Oxygenation-Related Optical Signal; Applications of phosphorescent O2 sensors in food and beverage packaging systems