Open-Channel Microfluidics
Fundamentals and applications
By (author) Jean Berthier, Ashleigh B Theberge, Erwin Berthier
Publication date:
28 August 2019Publisher
Morgan & Claypool PublishersISBN-13: 9781643276625
Open microfluidics – the study of microflows having a boundary with surrounding air – encompasses paper- or thread-based microfluidics, droplet microfluidics and open-channel microfluidics. Open-channel microflow is a flow at the micro-scale, guided by solid structures, and having at least a free boundary (with air or vapor) other than the advancing meniscus. This book is devoted to the study of open-channel microfluidics which, contrary to paper or thread or droplet microfluidics, is still very sparsely documented, but bears many new applications in biology, biotechnology, medicine, material and space sciences. Capillarity being the principal force triggering an open microflow, the principles of capillarity are first recalled. The onset of open-channel microflow is next analyzed and the fundamental notion of generalized Cassie angle – the apparent contact angle which accounts for the presence of air – is presented. The theory of the dynamics of open-channel microflows is then developed, using the notion of averaged friction length, which accounts for the presence of air along the boundaries of the flow domain. Different channel morphologies are studied and geometrical features, such as valves and capillary pumps, are examined. An introduction to two-phase open-channel microflows is also presented, showing that immiscible plugs can be transported by an open-channel flow. Finally, a selection of interesting applications in the domains of space, materials, medicine and biology is provided, showing the potentialities of open-channel microfluidics.